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Best Over-the-Counter Cystic Acne Treatments: Top Tips and Tricks (2024)

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Best over the counter treatments for cystic acneCystic acne is a serious form of acne that requires a strong treatment plan.

We’ve rounded up the best over-the-counter cystic acne treatments and tips for you to add to your skincare routine.

From foaming cleansers to spot treatments, these products will help clear your skin and prevent future breakouts.

Key Takeaways

  • Differin Adapalene Gel, CeraVe Acne Foaming Cleanser, PanOxyl Acne Foaming Wash, and Neutrogena Spot Treatment Gel are some of the best over-the-counter options for cystic acne.
  • Cystic acne can be influenced by diet, with foods like skim milk, whey protein, and high-sugar treats making it worse, and fatty fish like salmon helping to protect your skin.
  • Popping cystic acne is a no-go—it increases the risk of infection and scarring, and doesn’t get to the root of the problem.
  • Oral medications and injections, like spironolactone, isotretinoin, and cortisone injections, can be powerful tools to fight cystic acne when topicals aren’t enough.

Best Cystic Acne Treatments

If you’re looking for over-the-counter treatments for cystic acne, there are a few products worth considering. These include Differin Acne Treatment Gel, CeraVe Acne Foaming Cleanser, PanOxyl Acne Foaming Wash 10%, and Neutrogena Acne Spot Treatment Gel.

1. Differin Acne Treatment Gel

Differin Acne Treatment Gel, 30View On Amazon
Differin Adapalene Gel 0.1% is a prescription-strength retinoid available over the counter.

It helps to clear breakouts and prevent new acne formation by normalizing skin cell turnover and targeting clogged pores and inflammation.

This water-based, oil-free, alcohol-free, and fragrance-free gel is clinically proven to reduce acne breakouts by up to 87% after 12 weeks of consistent use.

It can also help reduce scarring and hyperpigmentation.

However, it may cause initial purging and skin sensitivity, so it’s important to use it sparingly and with caution, especially on sensitive areas like the eyelids and neck.

Best For: People with mild to moderate acne who are looking for a prescription-strength retinoid available over the counter.

Pros
  • Clinically proven to reduce acne breakouts by up to 87% after 12 weeks.
  • Helps to prevent new acne formation.
  • Can also help reduce scarring and hyperpigmentation.
Cons
  • May cause initial purging (increased acne).
  • Can cause skin sensitivity.
  • Requires consistent use for several weeks to see results.

2. CeraVe Acne Foaming Cleanser

CeraVe Acne Foaming Cream CleanserView On Amazon
CeraVe Acne Foaming Cleanser is a popular choice for managing cystic acne.

This cleanser contains 4% benzoyl peroxide, which helps to clear acne by removing excess oil and impurities from the skin’s surface while also penetrating deep into pores to target active breakouts.

The formula also includes ceramides, essential for maintaining the skin’s natural barrier, hyaluronic acid to attract hydration, and niacinamide to soothe the skin.

Users should be aware that this product may bleach colored washcloths and towels due to the benzoyl peroxide content, and it may not be suitable for sensitive skin types.

It’s recommended to follow up with a gentle moisturizer after using this cleanser, and it’s best not to combine it with retinol.

With its effective ingredients, gentle formula, and affordable price, CeraVe Acne Foaming Cleanser is a top choice for those seeking over-the-counter solutions for cystic acne.

Best For: CeraVe Acne Foaming Cleanser is best for those with cystic acne who are looking for a gentle yet effective cleanser.

Pros
  • Contains 4% benzoyl peroxide to effectively treat cystic acne.
  • Includes ceramides, hyaluronic acid, and niacinamide to maintain the skin’s barrier, hydrate, and soothe.
  • Affordable price for the amount of product received.
Cons
  • May bleach colored washcloths and towels.
  • May not be suitable for sensitive skin.
  • May leave skin feeling dry.

3. PanOxyl Acne Foaming Wash 10%

PanOxyl Acne Foaming Wash BenzoylView On Amazon
If you’re dealing with cystic acne, PanOxyl Acne Foaming Wash 10% is a great option.

This maximum-strength formula contains 10% benzoyl peroxide, the highest concentration available over the counter.

It’s an antimicrobial foaming wash that kills acne-causing bacteria on contact, helping to clear existing acne and prevent new blemishes.

It cleanses and unclogs pores on your face, chest, and back, and it also gently removes dirt and excess oil, leaving your skin feeling refreshed and clear.

This product is recommended by dermatologists and can be safely used on your face.

A little goes a long way, so use it sparingly and be cautious if you have sensitive skin.

Best For: This product is best for people with moderate to severe acne, particularly cystic acne.

Pros
  • Contains the highest over-the-counter concentration of benzoyl peroxide (10%) for effective acne treatment.
  • Kills acne-causing bacteria on contact, helping to clear existing acne and prevent new blemishes.
  • Cleanses and unclogs pores, leaving skin feeling refreshed and clear.
Cons
  • May be too strong for sensitive skin, potentially causing dryness or irritation.
  • May have a strong medicinal smell.
  • May bleach towels if not rinsed thoroughly.

4. Neutrogena Acne Spot Treatment Gel

Neutrogena Rapid Clear Stubborn AcneView On Amazon
If you’re looking for a spot treatment, consider Neutrogena’s Acne Spot Treatment Gel.

This gel contains 10% benzoyl peroxide, the acne-fighting ingredient dermatologists recommend the most.

It’s clinically proven to reduce the size and redness of acne in just two hours and can help prevent future breakouts.

The product is unscented, and you can apply it up to three times daily.

However, it may cause dryness or peeling, so start with a small amount and less frequent application to see how your skin reacts.

Best For: Those with stubborn acne looking for a fast-acting spot treatment.

Pros
  • Contains 10% benzoyl peroxide, a dermatologist-recommended acne-fighting ingredient.
  • Clinically proven to reduce acne size and redness in just two hours.
  • Helps prevent future breakouts.
Cons
  • May cause dryness or peeling.
  • May cause stinging.
  • Not suitable for all skin types.

What Causes Cystic Acne?

What Causes Cystic Acne
Cystic acne can be triggered by certain foods, like skim milk, whey protein, vitamin B12 supplements, and high-sugar foods. Stress and hormonal changes, particularly fluctuations in androgen hormones like testosterone, can also contribute to cystic acne flare-ups.

Food Triggers

What you eat can have a big impact on your skin.

Some foods can make cystic acne worse, like skim milk, whey protein, vitamin B12 supplements, and high-sugar foods.

You might find that limiting or avoiding dairy, eggs, and processed carbs helps your skin.

Almonds and walnuts are great "skin foods" because they’re packed with nutrients that help fight acne.

Berries are also great, as they’re full of antioxidants that prevent dark spots and keep skin clear.

And don’t forget about fatty fish like salmon, which is rich in omega-3 fatty acids that protect your skin from UV damage.

Stress and Hormones

Stress and hormones play a significant role in cystic acne. While scientists don’t know the exact mechanism, they do know that stress increases acne severity. Cells that produce sebum have receptors for stress hormones, leading to more oil clogging your hair follicles and causing breakouts. Hormone imbalances, especially fluctuations in estrogen, progesterone, and androgen, can also trigger cystic acne.

Popping Cystic Acne

Popping cystic acne is a big no-no.

Why? Well, for starters, you run the risk of infection and scarring.

Cystic acne is deep beneath the skin’s surface, so trying to pop it can cause more harm than good.

Plus, it’s not an effective treatment—it won’t cure your cystic acne.

Active Ingredients to the Rescue

Active Ingredients to the Rescue
Now that you know what causes cystic acne, let’s take a closer look at the active ingredients that can help fight those pesky bumps and blemishes. Here’s a breakdown of the key players in your acne-fighting arsenal:

  • Salicylic Acid: This beta hydroxy acid (BHA) is a powerhouse for tackling acne. It works by penetrating deep into your pores, helping to clear out excess oil, dead skin cells, and other gunk that can contribute to breakouts.
  • Benzoyl Peroxide: Think of this ingredient as your acne-fighting superhero. It attacks the bacteria that cause acne, reducing inflammation and helping to clear up those annoying lesions.
  • Adapalene: This topical retinoid is like a magic wand for your skin. By regulating cell turnover, it helps prevent your pores from becoming clogged in the first place.
  • Natural Alternatives: If you’re looking for a more natural approach, ingredients like tea tree oil and azelaic acid have been shown to effectively combat cystic acne. Tea tree oil has antimicrobial properties, while azelaic acid helps to normalize skin cell turnover and reduce inflammation.

Skincare Do’s and Don’ts

Skincare Do
When it comes to skincare for cystic acne, there are some important do’s and don’ts to keep in mind. Here are the key ones:

DO DON’T
Use a gentle cleanser twice a day to remove excess oil and dead skin cells without irritating your skin. Over-exfoliate or use harsh scrubs that can damage your skin’s barrier.
Opt for oil-free, noncomedogenic moisturizers to hydrate your skin without clogging pores. Forget to introduce new products slowly to assess skin tolerance and avoid potential irritation.
Keep your skincare routine simple, especially if you’re using multiple active ingredients. Neglect consulting a dermatologist for personalized advice and treatment options.
Be patient and consistent with your routine for the best results. Expect overnight miracles or quick fixes. Cystic acne treatment takes time and consistency.

Pro Tips: Popping Pimples

Pro Tips: Popping Pimples

  1. It’s Risky Business: Popping pimples, especially cystic acne, can increase your risk of infection and scarring. It’s just not worth the squeeze.
  2. Avoid the Spread: Popping pimples can also spread bacteria to other areas of your skin, causing more breakouts. It’s like playing a game of whack-a-mole with your acne—not fun!
  3. Over-the-counter spot treatments are your friend: Instead of popping, reach for an over-the-counter acne treatment with benzoyl peroxide or salicylic acid to help dry up the pimple and reduce inflammation.

Beyond Topicals: Oral and Injectable Treatments

Beyond Topicals: Oral and Injectable Treatments
While topical treatments are a great first step, sometimes cystic acne requires a more intensive approach. Oral medications and injections can be powerful tools in your acne-fighting arsenal.

Treatment Benefits
Spironolactone Blocks excess hormones that cause cystic acne
Isotretinoin Reduces inflammation and prevents new acne
Cortisone Injections Dries up cysts quickly

Spironolactone and isotretinoin are oral prescription medications that can be game-changers for cystic acne. Spironolactone works by blocking the excess hormones that contribute to acne breakouts. Isotretinoin, often known by the brand name Accutane, is a powerful medication that reduces inflammation and prevents new acne lesions from forming.

In addition to oral medications, in-office cortisone injections can be an effective tool for quickly shrinking cystic acne lesions. These injections deliver a concentrated dose of medication directly to the affected area, providing rapid relief.

Frequently Asked Questions (FAQs)

What is the most effective treatment for cystic acne?

Cystic acne is a beast, but it can be tamed. A dermatologist can prescribe oral antibiotics and topical gels or creams to zap those zits. Cortisone injections can shrink angry cysts.

What is the fastest way to get rid of a cystic pimple?

For quick results, try a cold compress to reduce inflammation, use a gentle cleanser, and apply a spot treatment containing benzoyl peroxide. A warm compress can also help bring the pimple to the surface.

What is the best routine for cystic acne?

Keep your skin clean and bacteria-free. Wash your face with a salicylic-acid face wash, then use a vitamin C serum to protect your skin and reduce the chance of pigmentation.

What is the drug of choice for cystic acne?

Spironolactone is a common drug choice for cystic acne. It blocks the production of androgens, such as testosterone, reducing oil production and lowering the frequency of clogged pores.

Can cystic acne be cured?

Cystic acne is challenging to cure. While over-the-counter products can help, they’re not strong enough to cure it. See a dermatologist for prescription treatments like cortisone injections or oral medication.

What foods make cystic acne worse?

Fried foods, baked goods, dried fruit, fruit juice, cocktails, mocktails, and skim milk can make cystic acne worse. These foods are linked to increased oil production, inflammation, and hormonal imbalances.

Does cystic acne always scar?

Cystic acne is the type of acne most likely to scar. The longer a cyst is left untreated, the more likely it’s to cause scarring. Picking or popping cysts can also increase the risk of scarring.

How do I prevent cystic acne?

Maintaining a strict skincare regimen is key to preventing cystic acne. Wash your face with a gentle cleanser twice daily and after sweating. Avoid touching your face and picking at blemishes.

Is cystic acne contagious?

No, cystic acne isn’t contagious. You can touch, hug, kiss, or share a towel with someone with cystic acne without the risk of developing pimples.

Conclusion

Tackling cystic acne calls for a heavy-duty game plan.

We’ve served up the best over-the-counter cystic acne treatments and tricks to add to your skincare arsenal.

From spot treatments to active ingredients, these tips will help banish those pesky bumps and prevent future flare-ups.

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Mutasim Sweileh

Mutasim is a published author and software engineer and beard care expert from the US. To date, he has helped thousands of men make their beards look better and get fatter. His work has been mentioned in countless notable publications on men's care and style and has been cited in Seeker, Wikihow, GQ, TED, and Buzzfeed.